产品介绍
Product Description
Biochem/physiol Actions
NSC59984 targets various mutant p53 to restore wild-type p53 pathway via the activation of p73 in cancer cells.
NSC59984 targets various mutant p53 to restore wild-type p53 pathway via the activation of p73 in cancer cells. NSC59984 depletes a gain of function (GOF p53 mutants. NSC59984 is not cytotoxic against normal cells.
技术参数
Specifications
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | yellow to brown |
| solubility | DMSO: 5 mg/mL, clear (warmed) |
| storage temp. | 2-8°C |
| SMILES string | CN1CCN(C(/C=C/C2=CC=C([N+]([O-])=O)O2)=O)CC1 |
| InChI | 1S/C12H15N3O4/c1-13-6-8-14(9-7-13)11(16)4-2-10-3-5-12(19-10)15(17)18/h2-5H,6-9H2,1H3/b4-2+ |
| InChI key | QKTRIGNWBRHBFV-DUXPYHPUSA-N |
