General description
Ribonuclease/angiogenin inhibitor 1 (RNH1) is a cytoplasmic protein ubiquitously produced in all organs except testis. Rnh1 was first isolated from human placenta. The gene RNH1 is located in the human chromosome on 11p15.5.
Immunogen
Synthetic peptide directed towards the middle region of human RNH1
Biochem/physiol Actions
Ribonuclease/angiogenin inhibitor 1 (RNH1) has several leucine rich repeats which aids them in protein-protein interaction. Rnh1 binds with greater affinity and reversibly to members of ribonuclease 1 (RNase 1). Rnh1 has high affinity to angiogenin and inhibits its angiogenic functionality.
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Other Notes
Synthetic peptide located within the following region: LLHPSSRLRTLWIWECGITAKGCGDLCRVLRAKESLKELSLAGNELGDEG
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | 50 kDa |
| species reactivity | rat, human |
| concentration | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI accession no. | NM_203387 |
| UniProt accession no. | P13489 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... RNH1(6050) |
