产品介绍
Product Description
Application
在杂交瘤形成应用中作为选择剂。
Biochem/physiol Actions
核糖基化并通过与天然嘌呤碱相同的途径磷酸化；作为核苷酸，抑制参与核酸合成的多种细胞过程。作为白血病的有效治疗方法已有悠久的历史。
Preparation Note
10mL 无菌细胞培养基可复原一小瓶本品。储存液足以制备 500mL 培养基。最终工作浓度：30μM 2-氨基-6-巯基嘌呤。
Legal Information
Hybri-Max is a trademark of Sigma-Aldrich Co. LLC
技术参数
Specifications
| biological source | synthetic (organic) |
| Quality Level | 200 |
| grade | Hybri-Max™ |
| sterility | γ-irradiated |
| product line | BioXtra |
| assay | ~98% |
| form | lyophilized powder |
| concentration | 50 × |
| technique(s) | cell culture | hybridoma: suitable |
| impurities | endotoxin, tested |
| mp | ≥300 °C (lit.) |
| solubility | 1 M NaOH: 50 mg/mL, clear to slightly hazy |
| web metadata keyword.default | Selection agent, purine antimetabolite, thiopurine, mutagen, cytotoxin |
| storage temp. | room temp |
| SMILES string | NC1=Nc2nc[nH]c2C(=S)N1 |
| InChI | 1S/C5H5N5S/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11) |
| InChI key | WYWHKKSPHMUBEB-UHFFFAOYSA-N |
| Gene Information | human ... IMPDH1(3614), IMPDH2(3615) |
