产品介绍
Product Description
Application
SR 57227A may be used in 5-HT3-mediated cell signaling studies.
Biochem/physiol Actions
Potent and selective 5-HT3 serotonin receptor agonist.
SR 57227A is a highly selective of central and peripheral 5-HT3 receptors and an inhibitor of NMDA receptor-mediated responses in rat cortical pyramidal cells. It exhibits anti-depressant like effects in rats and decreased isolation-induced aggressive behavior.
技术参数
Specifications
| form | solid |
| Quality Level | 100 |
| color | white |
| solubility | H2O: soluble 9 mg/mL |
| SMILES string | Cl.NC1CCN(CC1)c2cccc(Cl)n2 |
| InChI | 1S/C10H14ClN3.ClH/c11-9-2-1-3-10(13-9)14-6-4-8(12)5-7-14;/h1-3,8H,4-7,12H2;1H |
| InChI key | FUMINTAAUJUVMP-UHFFFAOYSA-N |
| Gene Information | human ... HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242) |
