产品介绍
Product Description
Biochem/physiol Actions
AC-93253 is a potent, cell permeable, subtype selective RAR (RARα) agonist. EC50 = 6.3 μM. AC-93253 has high selectivity; 89% for RARα vs 67% for RARβ1, 35% for RARβ2, and 11% for RARγ.
Potent, cell permeable, subtype selective RAR (RARα) agonist.
Features and Benefits
This compound is featured on the Nuclear Receptors (Non-Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
技术参数
Specifications
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | solid |
| storage condition | desiccated |
| color | dark purple |
| solubility | DMSO: >10 mg/mL,H2O: insoluble |
| storage temp. | 2-8°C |
| SMILES string | [I-].CC[n+]1c(\C=C\C=C2\N(C)c3ccccc3C2(C)C)sc4ccccc14 |
| InChI | 1S/C23H25N2S.HI/c1-5-25-19-13-8-9-14-20(19)26-22(25)16-10-15-21-23(2,3)17-11-6-7-12-18(17)24(21)4;/h6-16H,5H2,1-4H3;1H/q+1;/p-1 |
| InChI key | TWBRXRGFFUATNI-UHFFFAOYSA-M |
