产品介绍
Product Description
Biochem/physiol Actions
KI-ARv-03 is a cell penetrant, potent and selective inhibitor of CDK9 that that reduces AR-driven transcription and proliferation in prostate cancer cells. KI-ARv-03 modulates AR and AR-V7-dependent transcription in 22Rv1 cells. It exhibits potent anti-tumor activity in castration-resistant prostate cancer (CRPC) models.
Orally available, potent, ultraselective CDK9 inhibitor that exhibits potent anti-tumor activity in castration-resistant prostate cancer (CRPC) models
技术参数
Specifications
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | (Powder or Lyophilized powder or film or oil) |
| color | colorless to brown-yellow |
| storage temp. | 2-8°C |
| SMILES string | CCCC1=NC2=CC=NN2C(N[C@H]3C[C@@H](CC3)N)=C1 |
