General description
Disodium salt
Application
Substrate for glucose-6-phosphatase.
Biochem/physiol Actions
In mammals, glucose-6-phosphate (G6P) is formed by a kinase acting on glucose. It plays several roles and has its fate determined accordingly. It can get converted back to glucose by a phosphatase enzyme. It can pass into glycogen, or enter into the energy-yielding Embden-Meyerhof path or into the 6-phosphogluconate pathway. Increased levels of blood glucose result in elevated levels of glucose 6-phosphate in liver, skeletal muscle, and adipose tissue. This elevated intracellular level of G6P activates glycogen synthase. G6P may also be involved in the negative regulation of phosphorylation of glycogen synthase via cyclic AMP-stimulated protein kinase.
Preparation Note
77% glucose-6-P (enzymatic), 13% sodium, 8% water
C6H11O9PNa2
Analysis Note
Contaminants: <0.2% glucose (enzymatic)
Other Notes
仅用于生命科学研究。不可用于诊断。
| form | solid |
| mol wt | (glucose-6-P: Mr = 260.2, glucose-6-P-Na2: Mr = 304.2) |
| packaging | pkg of 5 g |
| manufacturer/tradename | Roche |
| shipped in | ambient |
| SMILES string | O.[Na+].[Na+].OC1O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@H](O)[C@H]1O |
| InChI | 1S/C6H13O9P.2Na.H2O/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8;;;/h2-10H,1H2,(H2,11,12,13);;;1H2/q;2*+1;/p-2/t2-,3-,4+,5-,6?;;;/m1.../s1 |
| InChI key | UUWJZXLTPORJKW-WYFATIGWSA-L |
