产品介绍
Product Description
Application
AC-265347 may be used in calcium-sensing receptor-mediated signaling.
Biochem/physiol Actions
AC-265347 is a calcimimetic that acts as agonist to calcium-sensing receptor. It reduces serum parathyroid hormone and plasma ionizable calcium.
AC-265347 is a human calcium-sensing receptor (CaSR) allosteric agonist. AC-265347 activates CaSR signaling in cellular proliferation and phosphatidyl inositol (PI) hydrolysis assays.
AC-265347 is a human calcium-sensing receptor (CaSR) allosteric agonist; calcimimetic
技术参数
Specifications
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to tan |
| solubility | DMSO: ≥19 mg/mL |
| storage temp. | 2-8°C |
| SMILES string | Cc1ccc(c(C)c1)C(C)(O)c2nc3ccccc3s2 |
| InChI | 1S/C17H17NOS/c1-11-8-9-13(12(2)10-11)17(3,19)16-18-14-6-4-5-7-15(14)20-16/h4-10,19H,1-3H3 |
| InChI key | IGSZVEPQZANNAB-UHFFFAOYSA-N |
