产品介绍
Product Description
Application
5-Pregnen-3β-ol-20-one-16α-carbonitrile has been used:
- in the induction of cytochrome P450
- as pregnane X receptor (PXR) activator in human liver cell lines.
Biochem/physiol Actions
Pregnenolone-16a-carbonitrile (PCN) is a glucocorticoid receptor antagonist and a PXR (pregnane X receptor) activator.
技术参数
Specifications
| biological source | synthetic (organic) |
| Quality Level | 100 |
| sterility | non-sterile |
| assay | ≥97% |
| form | powder, crystals or chunks |
| technique(s) | cell culture | mammalian: suitable |
| solubility | chloroform: methanol (1:1): 50 mg/mL, clear, colorless to faintly yellow (with heat) |
| shipped in | ambient |
| storage temp. | 2-8°C |
| SMILES string | C[C@@]12[C@](C[C@@H](C#N)[C@@H]2C(C)=O)([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC1 |
| InChI | 1S/C22H31NO2/c1-13(24)20-14(12-23)10-19-17-5-4-15-11-16(25)6-8-21(15,2)18(17)7-9-22(19,20)3/h4,14,16-20,25H,5-11H2,1-3H3/t14-,16-,17+,18-,19-,20-,21-,22-/m0/s1 |
| InChI key | VSBHRRMYCDQLJF-ZDNYCOCVSA-N |
