General description
Anti-GFAP Antibody detects endogenous levels of total GFAP protein.
Glial fibrillary acidic protein (GFAP) is an intermediate-filament protein found in the astrocytes of CNS (central nervous system). It is located on human chromosome 17q21.
Immunogen
The antiserum was produced against synthesized peptide derived from human GFAP.
Immunogen Range: 11-60
Application
Anti-GFAP, N-Terminal antibody has been used in immunocytochemical analysis , confocal and fluorescent microscopic imaging , immunostaining and western blotting.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)
Biochem/physiol Actions
Glial fibrillary acidic protein (GFAP) regulates intermediate filament network dynamics, cell morphology and focal adhesions.It helps in maintaining myelination and stability of CNS (central nervous system) white matter architecture.
Features and Benefits
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Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | antigen 49 kDa |
| species reactivity | human |
| concentration | ~1 mg/mL |
| technique(s) | ELISA: 1:1000,immunofluorescence: 1:100-1:500,immunohistochemistry: 1:50-1:100,western blot: 1:500-1:1000 |
| NCBI accession no. | P14136 |
| UniProt accession no. | P14136 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... GFAP(2670) |
