规格
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Accession Number:
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NP_079052 |
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Protein Form:
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Recombinant, Active, Catalytic |
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Shipping Condition:
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Dry Ice |
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Molecular Weight:
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96.3 kDa |
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Validated Application:
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Kinase Assay |
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Expression System:
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Insect |
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KinaseFamily:
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NKF3 Family |
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Protein Length:
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aa 1127 - end |
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Protein Tag:
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GST Tag |
储存
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Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. |
This PEAK1 recombinant human protein (1127–end) was expressed in insect cells. PEAK1 cytoplasmic tyrosine kinase or Pseudopodium-enriched atypical kinase 1 is a protein tyrosine kinase which belongs to NKF3 kinase family and regulates the cytoskeleton and has been shown to be involved in cancer progression. PEAK1 promotes anchorage-independent growth in the MDA-MB-435 human cancer cell line and promotes tumor progression of XPA-1 human pancreatic cancer cells when transplanted into the pancreas of nude mice. PEAK1 is highly expressed in spleen, followed by heart, ovary, brain, lung, kidney, and fetal brain. PEAK1 recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.
• Validated for use with the Z’-LYTE™ assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service
