产品介绍
Product Description
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规格 |
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| Accession Number: | NM_005855.2 |
| Assay Entry: | Cell-based beta lactamase reporter gene |
| Cell Line: | FreeStyle™ 293-F Cells |
| Cell State: | Dividing Cells |
| Druggable Target: | GPCRs |
| Gene Symbol: | CALCRL:RAMP1 |
| Population Status: | Single Cell Clone Origin |
| Product Line: | Freestyle™, GeneBLAzer® |
| Reporter Gene: | BLA (Beta-Lactamase) |
| System Type: | GeneBLAzer™ |
| Target Entry: | CALCRL:RAMP1 |
| Detection Method: | Fluorescent |
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储存 |
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(LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol). Includes: • GeneBLAzer® CALCRL:RAMP1-CRE-bla Freestyle™ 293F cells • GeneBLAzer® CALCRL:RAMP1-CRE-bla Freestyle™ 293F Assay Protocol • Certificate of Analysis The GeneBLAzer® CALCRL:RAMP1-CRE-bla Freestyle™ 293F cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt. |
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描述 |
GeneBLAzer® CALCRL:RAMP1-CRE-bla FreeStyle™ 293F cells contain the human Calcitonin Gene Related Peptide Receptor (CALCRL:RAMP1), (Accession # NM_005795.3 NM_005855.2) stably integrated into the CellSensor® CRE-bla Freestyle™ 293F cell line. CellSensor® CRE-bla Freestyle™ 293F cells (Cat # K1130) contain a beta-lactamase (bla) reporter gene under control of the cAMP response element (CRE).
CALCRL:RAMP1-CRE-bla FreeStyle™ 293F cells are functionally validated for Z'-factor and EC50 concentrations of Alpha-CGRP. In addition, CALCRL:RAMP1-CRE-bla FreeStyle™ 293F cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary in the Manuals and Brochures section.
