产品介绍
Product Description
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规格 |
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| Accession Number: | NP_004963 |
| Kinase Group: | Tyrosine Kinases |
| Shipping Condition: | Dry Ice |
| Expression System: | Baculovirus |
| Form: | Frozen |
| Protein Form: | Catalytic |
| Research Category: | Drug Development |
| Species: | Human |
| Validated Application: | Kinase Assay |
| Molecular Weight: | 97.9 kDa |
| Gene Alias: | JAK2 JH1 JH2 V617F |
| KinaseFamily: | JAK Kinase Family |
| Protein Tag: | GST Tag |
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储存 |
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Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws. |
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描述 |
JAK2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. This kinase contains both the JH1 (catalytic) and JH2 (pseudokinase) domains of JAK2. The V617F mutation has been shown to be a cause of polycythemia vera.
