产品介绍
Product Description
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规格 |
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| Accession Number: | NP_004926.1 I NP_003876 |
| Assay Entry: | Biochemical binding/kinetic, Biochemical phospho-specific activity (no antibody) |
| Kinase Group: | Ser⁄Thr Kinases: CMCG Group |
| Shipping Condition: | Dry Ice |
| System Compatibility: | Z'-LYTE™ |
| Target Entry: | CDK5 |
| Target Gene: | cyclin-dependent kinase 5 |
| Expression System: | Baculovirus |
| Protein Family: | Kinases & Inhibitors |
| Protein Form: | Full Length, Recombinant |
| Protein Subtype: | Serine⁄Threonine Kinases |
| Research Category: | Cell Cycle & Proliferation, Signal Transduction |
| Species: | Human |
| Validated Application: | Kinase Assay |
| Molecular Weight: | 36.7⁄51.0 kDa |
| Gene Alias: | CDK5/p25, CDK5R |
| KinaseFamily: | CDK and CHK Kinase Family |
| Protein Tag: | GST Tag, His Tag |
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储存 |
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Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% Glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws. |
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描述 |
CDK5 plays a critical role in neuron development. The disregulation of the CDK5 and the truncated activator p25 is believed to be involved in neurodegenerative diseases such as Alzheimer's, Parkinson's, and Amyotrophic Lateral Sclerosis. This protein is coexpressed and copurified with p25.
