产品介绍
Product Description
Clone REA734 recognizes the human CD8 antigen, a cell-surface glycoprotein also known as Leu-2 or CD8a. CD8 is strongly expressed on human cytotoxic T cells and thymocytes as well as on a subset of natural killer (NK) cells. The CD8 antigen is a disulfide-linked dimer that exists either as a CD8a homodimer or as a CD8α/β heterodimer. CD8 acts as a coreceptor for the T cell receptor and binds to the MHC class I molecules. CD8 is involved in T cell development and activation of mature T cells. The CD8 antibody recognizes the α-subunit of the antigen.
Additional information: Clone REA734 displays negligible binding to Fc receptors.
Leu-2, CD8a, MAL, p32, Ly-2, LY3, Lyt3, P37
Technical specifications
