规格
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Accession Number:
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NP_005019.2 |
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Protein Form:
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Full Length, Recombinant, Active |
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Shipping Condition:
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Dry Ice |
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Molecular Weight:
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72.5 kDa |
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Validated Application:
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Kinase Assay |
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Expression System:
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Insect |
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KinaseFamily:
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PI3 Kinase |
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Protein Length:
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Full Length |
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Protein Tag:
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GST Tag |
储存
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Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol |
This PIP4K2A recombinant human protein (full length) was expressed in insect cells. PIP4K2A lipid kinase or phosphatidylinositol-5-phosphate 4-kinase, type II, alpha, is a member of the phosphatidylinositol-5-phosphate 4-kinase family that catalyzes the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-4,5-bisphosphate. PIP4K2A plays as essential role in the phosphoinositide signal transduction cascades as the precursor to second messengers and is involved in the regulation of secretion, cell proliferation, differentiation, and motility. PIP4K2A may be one of the factors related to the regulation of the beta-globin gene expression and the different levels of Hb H in alpha-thalassemic patients. PIP4K2A recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.
• Validated for use with the Adapta™ assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service
