规格
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Crosslinker Type:
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Heterobifunctional |
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Labeling Method:
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Chemical Labeling |
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Product Line:
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Pierce™ |
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Reactive Moiety:
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Maleimide, NHS Ester |
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Spacer:
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Long |
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Solubility:
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DMSO (Dimethylsulfoxide), DMF (Dimethylformamide) |
储存
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Upon receipt store desiccated at 4°C. Product is shipped at ambient temperature. |
Thermo Scientific Pierce SMPH is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a long spacer arm (14.2 angstroms).
Features of SMPH:
• Reactive groups: NHS ester and maleimide
• Reactive towards: amino and sulfhydryl groups
• Slightly longer and more soluble than SMPB
• NHS ester reacts with primary amines at pH 7-9, forming a stable amide bond
• Maleimide reacts with -SH groups at pH 6.5-7.5, forming a stable thioether bond
• Non-cleavable
• Water-insoluble (dissolve first in DMF or DMSO)
Product References:
Crosslinker Application Guide -- search for recent literature references for this product
Related Products
SMPH (Succinimidyl 6-((beta-maleimidopropionamido)hexanoate))
