产品介绍
Product Description
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规格 |
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| Accession Number: | NP_066124, V804L |
| Kinase Group: | Tyrosine Kinases |
| Shipping Condition: | Dry Ice |
| Expression System: | Baculovirus |
| Form: | Frozen |
| Protein Form: | Cytoplasmic |
| Research Category: | Drug Development |
| Species: | Human |
| Validated Application: | Kinase Assay |
| Molecular Weight: | 79 kDa |
| Gene Alias: | RET V804L |
| KinaseFamily: | RET Kinase Family |
| Protein Tag: | GST Tag |
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储存 |
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Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws. |
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描述 |
The receptor tyrosine kinase RET is a member of the cadherin superfamily. RET plays a crucial role in neural crest development, and can undergo oncogenic activation by cytogenetic rearrangement. The V804L mutant has been observed in association with cancer.
