产品介绍
Product Description
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规格 |
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| Accession Number: | NP_004324.2 |
| Form: | Frozen |
| Kinase Group: | Ser⁄Thr Kinases: TKL Group |
| Protein Form: | Full Length |
| Research Category: | Drug Development |
| Shipping Condition: | Dry Ice |
| Species: | Human |
| Molecular Weight: | 113.6 kDa |
| Gene Alias: | BRAF, BRAF1 |
| Validated Application: | Kinase Assay |
| Expression System: | Baculovirus |
| KinaseFamily: | RAF Kinase Family |
| Protein Tag: | GST Tag |
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储存 |
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Storage Buffer: 50mM Tris, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws. |
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描述 |
BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It is activated by somatic point mutation in human cancer, and is thought to play a role in the postsynaptic responses of hippocampal neuron.
