规格
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Accession Number:
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NP_001165774 |
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Protein Form:
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Full Length, Recombinant |
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Shipping Condition:
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Dry Ice |
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Molecular Weight:
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123.6 kDa |
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Validated Application:
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Kinase Assay |
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Expression System:
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Insect |
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KinaseFamily:
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MAST Family |
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Protein Length:
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Full Length |
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Protein Tag:
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GST Tag |
储存
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Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. |
This MASTL recombinant human protein (full length) was expressed in insect cells. MASTL or microtubule associated serine/threonine kinase-like belongs to the MAST family, AGC Ser/Thr protein kinase group. MASTL promotes mitotic progression and cell cycle reentry after DNA damage. Loss of MASTL leads to defects in chromosome condensation, separation, and other aspects of mitotic progression, which is primarily mediated by inhibiting PP2A/B55 delta. Overexpression of MASTL is correlated with cancer progression, poor patient survival, and tumor recurrence in various cancers. MASTL recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.
• Validated for use with the LanthaScreen™ Eu Kinase Binding assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service
