产品介绍
Product Description
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规格 |
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| Accession Number: | AAH75064 |
| Kinase Group: | Ser⁄Thr Kinases: Other |
| Shipping Condition: | Dry Ice |
| System Compatibility: | Zin-LYTE™, Omnia® Bulk Substrate |
| Target Gene: | aurora kinase C |
| Expression System: | Baculovirus |
| Protein Family: | Kinases & Inhibitors |
| Protein Form: | Full Length, Recombinant |
| Protein Subtype: | Serine⁄Threonine Kinases |
| Research Category: | Oncology, Signal Transduction |
| Species: | Human |
| Validated Application: | Kinase Assay |
| Gene ID (Entrez): | 10488, 6795 |
| Molecular Weight: | 61.7 kDa |
| Gene Alias: | AURKC (Aurora C), Aurora A, STK13 |
| KinaseFamily: | Aurora Kinase Family |
| Protein Tag: | GST Tag |
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储存 |
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Storage Buffer: 50mM Tris, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws. |
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描述 |
AURKC (Aurora C) is a chromosomal passenger protein that forms complexes with AURKB (Aurora B) and inner centromere proteins, playing a role in organizing microtubules in relation to centrosome⁄spindle function during mitosis. It is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction.
