产品介绍
Product Description
Clone REA978 recognizes the human CD64 antigen, a high affinity Fc receptor for IgG, also known as FcγRI. CD64 contains three Ig-like domains in its extracellular domain and binds both monomeric and aggregated IgG and contributes to antibody-dependent cellular cytotoxicity (ADCC), phagocytosis, and the clearance of immune complexes. It is constitutively expressed on macrophages, monocytes, and eosinophils and can be up-regulated on neutrophils during infection or after stimulation with IFN-γ and colony-stimulating factors G-CSF and GM-CSF.
Additional information: Clone REA978 displays negligible binding to Fc receptors.
FCGR1A, CD64A, FcR I, IGFR1, FcγRI
Technical specifications
