产品介绍
Product Description
Clone REA670 recognizes the human variable beta 5.3 subunit of the α/β T cell receptor (TCR Vβ5.3), a member of the Ig superfamily. The TCR is a heterodimeric glycoprotein associated with the CD3 antigen. The α and β TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. TCR Vβ5.3 is a variant of the TCR β chain. α/β T cells express a diverse α/β TCR repertoire that specifically co-recognizes self or foreign antigen bound to antigen-presenting molecules, which thereby leads to T cell–mediated immunity. TCR Vβ5.3 is expressed on a subset of peripheral blood T cells.
Additional information: Clone REA670 displays negligible binding to Fc receptors.
TCR Vbeta5.3, TCR Vb5.3
Technical specifications
