General description
Native apotransferrin from human plasma. Substantially iron-free. Cell culture tested. Transferrin is a major iron binding protein and is found in human plasma or serum at concentrations of 3 mg/ml. Its concentration correlates with the total iron binding capacity of serum and its level is regulated by the availability of iron. It has bacteriostatic and fungistatic activity and is essential for iron utilization by the hemin-synthesizing reticulocytes. Stored in bone marrow as Tf-bound iron. Has a pI of 5.8.
Native apotransferrin from human plasma. Transferrin is a serum protein involved in iron binding and transport. Substantially iron-free. Cell culture-tested.
Physical form
Lyophilized from 10 mM phosphate buffer, pH 7.4.
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 year at -20°C.
Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
| description | Merck USA index - 14, 9571 |
| Quality Segment | 100 |
| assay | ≥95% (SDS-PAGE) |
| form | lyophilized |
| manufacturer/tradename | Calbiochem® |
| storage condition | OK to freeze |
| impurities | Endotoxins, none detected |
| pI | 5.8 |
| solubility | water: 10 mg/mL |
| cation traces | Fe: ≤0.01% |
| storage temp. | −20°C |
