产品介绍
Product Description
General description
A potent thiazolinedione (TDZ) type anti-hyperglycemic agent and a selective peroxisome proliferator-activated receptor γ (PPARγ) agonist (EC50 = 3 µM).
Biochem/physiol Actions
Cell permeable: no
EC50 = 3 µM as PPARγ agonist
Primary Target
Selective PPARγ agonist
Product does not compete with ATP.
Reversible: no
Preparation Note
Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Jha, R.J. 1999. Clin. Exp. Hypertens. 21, 157.
Xin, X., et al. 1999. J. Biol. Chem. 274, 9116.
Lohrke, B., et al. 1998. J. Endocrinol. 159, 429.
Willson, T.M., et al. 1996. J. Med. Chem. 39, 665.
Cantello, B.C., et al. 1994. J. Med. Chem. 37, 3977.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Harmful (C)
技术参数
Specifications
| Quality Segment | 100 |
| description | RTECS - XJ5813700 |
| assay | ≥98% (HPLC) |
| form | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition | OK to freeze |
| color | tan |
| solubility | DMSO: ≥25 mg/mL,ethanol: ≥25 mg/mL |
| shipped in | ambient |
| storage temp. | 2-8°C |
| InChI | 1S/C18H23NO3S/c1-18(9-3-2-4-10-18)12-22-14-7-5-13(6-8-14)11-15-16(20)19-17(21)23-15/h5-8,15H,2-4,9-12H2,1H3,(H,19,20,21) |
| InChI key | YZFWTZACSRHJQD-UHFFFAOYSA-N |
