General description
Urokinase plasminogen activator receptor-associated protein (uPARAP/Endo180/MRC2) is a member of the macrophage mannose receptor family of endocytic transmembrane glycoproteins. UPAR-Associated Protein is a membrane protein involved in matrix turnover during tissue remodeling, particularly the uptake and intracellular degradation of collagen, (Sulek, 2007).
~ 180 kDa
Immunogen
uPAR D3-tagged recombinant protein corresponding to human UPAR-Associated Protein.
Application
Anti-UPAR-Associated Protein Antibody, clone 2.h.9:F12 is an antibody against UPAR-Associated Protein for use in WB, IH.
Biochem/physiol Actions
The antibody recognizes UPAR-Associated Protein.
Physical form
Format: Purified
Analysis Note
Control
U937 cell lysate
Evaluated by Western Blot in U937 cell lysate.
Western Blot Analysis: 0.2 µg/ml of this antibody detected UPAR-Associated Protein on 10 µg of U937 cell lysate.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
| biological source | mouse |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | 2.h.9:F12, monoclonal |
| species reactivity | human, mouse |
| technique(s) | immunohistochemistry: suitable,western blot: suitable |
| isotype | IgG1κ |
| NCBI accession no. | NP_006030.2 |
| UniProt accession no. | Q9UBG0 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... MRC2(9902) |
