产品介绍
Product Description
General description
EGFR
N末端带有GST标签的重组人EGFR，氨基酸696末端，包含突变T790M和L858R
Application
研究子类别
肥胖症
代谢紊乱
骨质疏松症
关节炎
研究类别
代谢
炎症 & 免疫学
Biochem/physiol Actions
蛋白质靶标：EGFR
靶标亚家族：TK
Packaging
另提供10 μg装和散装形式
Physical form
谷胱甘肽琼脂糖
Preparation Note
自发货之日起可在-70°C保存6个月
Analysis Note
通过250 μM底物肽（GGMEDIYFEFMGGKKK）的磷酸化进行常规评估
Other Notes
比活相关数据，请参阅检验报告以获取该酶的单独批次。
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
技术参数
Specifications
| biological source | human |
| Quality Segment | 100 |
| recombinant | expressed in baculovirus infected Sf21 cells |
| product line | Upstate® |
| specific activity | (For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.) |
| mol wt | Mw 85.8 kDa |
| purified by | (Glutathione-agarose) |
| species reactivity | human |
| manufacturer/tradename | Upstate® |
| technique(s) | activity assay: suitable |
| accession no. | (FUNCTION: SwissProt: P00533 # Isoform 2/truncated isoform may act as an antagonist. ),NM_005228.3 |
| NCBI accession no. | NM_005228.3,NM_201282.1,NM_201283.1,NM_201284.1 |
| UniProt accession no. | P00533 |
| relevant disease(s) | arthritis; obesity; osteoporosis; metabolic disorders |
