General description
Immunoglobin M (IgM) antibody is prominent in early immune responses to most antigens and is the predominant response in certain antibody responses such as "natural" blood group antibodies. IgM is the major immunoglobin expressed on surface B lymphocytes. Most of the chronic lymphocytic leukemias, non Hodgkin lymphomas and Burkitt′s lymphoma bear surface IgM, whereas plasmocytes from Waldenström′s disease bear intracytoplasmic IgM.
50 kDa calculated
Immunogen
Epitope: IgM, (Fc)
Human anti-Human IgM (myeloma) Fc5u fragment
Application
Research Category
Secondary & Control Antibodies
Research Sub Category
Isotype Control Antibodies
Sheep anti-Human IgM, (Fc) Antibody is an antibody against Human IgM, (Fc) for use in ELISA.
Biochem/physiol Actions
No reactivity with IgG or IgA. May react with IgM of other species with low specificity.
This antibody reacts with human IgM, (Fc) as demonstrated by ELISA.
Physical form
Depletion
Format: Purified
Purified sheep polyclonal in PBS containing 0.05% sodium azide. Depleted against rabbit IgM and human IgG.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control
Human IgG, Human IgG Fab Fragment, Human IgG Fc, Human IgM Fc, Human IgM (myeloma) Fab m fragment, Human IgA, Mouse IgM, Rat IgM whole molecule, Chicken IgM whole molecule, Goat IgM whole molecule, Guinea Pig IgM whole molecule, Hamster IgM whole molecule, and Rabbit IgM whole molecule
Evaluated by ELISA against Human IgG, Human IgG Fab Fragment, Human IgG Fc, Human IgM Fc, Human IgM (myeloma) Fab m fragment, Human IgA, Mouse IgM, Rat IgM whole molecule, Chicken IgM whole molecule, Goat IgM whole molecule, Guinea Pig IgM whole molecule, Hamster IgM whole molecule, and Rabbit IgM whole molecule.
ELISA Analysis: A representative lot detected Sheep Anti-Human IgM, (Fc) in ELISA.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | sheep |
| Quality Segment | 100 |
| antibody form | purified antibody |
| antibody product type | secondary antibodies |
| clone | polyclonal |
| species reactivity | human |
| manufacturer/tradename | Chemicon® |
| technique(s) | ELISA: suitable |
| shipped in | wet ice |
| target post-translational modification | unmodified |
