General description
109 kDa calculated
Myosin XIX (Myo19) is the founding member of a novel class of myosin that associates with mitochondria. Both endogenous Myo19 and GFP-Myo19 exihibit localization to mitochondria. Myosins are actin-based motor molecules with ATPase activity. Myo19 is involved in actin-based mitochondrial motility. Myo19 mRNA is expressed in multiple tissues, and antibodies to human Myo19 detect an approximately 109 kDa band in multiple cell lines.
Immunogen
KLH-conjugated linear peptide corresponding to human Myosin XIX (Myo19).
Application
Anti-Myosin XIX (Myo19) Antibody detects level of Myosin XIX (Myo19) & has been published & validated for use in IH(P).
Biochem/physiol Actions
Other homologies: Rat and Mouse (92% sequence homology).
Analysis Note
Evaluated by Immunohistochemistry in human cardiac muscle tissue.
Immunohistochemistry Analysis: A 1:50 dilution of this antibody detected Myosin XIX (Myo19) in human cardiac muscle tissue.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| purified by | affinity chromatography |
| species reactivity | human |
| species reactivity (predicted by homology) | canine (based on 100% sequence homology) |
| technique(s) | immunohistochemistry: suitable (paraffin) |
| NCBI accession no. | NP_001028752 |
| UniProt accession no. | Q96H55 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... MYO19(80179) |
