General description
IgM constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and predominates in certain antibody responses such as ′natural′ blood group antibodies. IgM (with IgD) is the major immunoglobulin expressed on the surface of B cells. The gene for the mu constant region contains four domains separated by short intervening sequences.
Application
This Goat anti-Mouse IgM µ chain Antibody, Species Adsorbed is validated for use in ELISA for the detection of Mouse IgM µ chain.
Biochem/physiol Actions
Reacts with heavy chain of mouse IgM. Absorbed for mouse IgG1, IgG2a, IgG2b, IgG3 and IgA, pooled human sera and purified human paraproteins. Minimal cross reactivity with human immunoglobulins. Reactivity with other species has not been determined.
Physical form
Purified by affinity chromatography on mouse IgM covalently linked to agarose. Liquid in 1.0 mL of 100 mM borate buffered saline, pH 8.2.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
| biological source | goat |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity purified immunoglobulin |
| antibody product type | secondary antibodies |
| clone | polyclonal |
| species reactivity | mouse |
| manufacturer/tradename | Chemicon® |
| concentration | 1 mg/mL |
| technique(s) | ELISA: suitable |
| shipped in | wet ice |
| target post-translational modification | unmodified |
