General description
300-500 kDa
The product of this gene belongs to the plakin or cytolinker family of genes. The encoded protein is involved in cytoskeleton-membrane attachment in epithelial cells, muscle, and other tissues. It also may regulate changes of lymphocyte cytoarchitecture during polarization and extravasation. This gene has alternative splicing of different 5′ exons to the first constant exon, which generates transcript variants that encode distinct isoforms
Immunogen
Gel-purified C5 Cell plectin
Application
Detect Plectin using this Anti-Plectin Antibody, Clone 10F6 validated for use in WB, IH.
Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Neuronal & Glial Markers
Biochem/physiol Actions
Cat. # MAB5674 recognizes the cytoplasmic domain of Plectin.
Reactivity with other species has not been tested.
Physical form
Format: Purified
Purified in PBS with 0.05% NaN3
Preparation Note
Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.
Analysis Note
Control
rat brain tissue lysate
Routinely tested on rat brain tissue lysate
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | mouse |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | purified antibody |
| antibody product type | primary antibodies |
| clone | 10F6, monoclonal |
| species reactivity | mouse, human, rat |
| manufacturer/tradename | Chemicon® |
| technique(s) | immunohistochemistry: suitable,western blot: suitable |
| UniProt accession no. | P30427 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... ACTC1(70), ACTG1(71) |
