General description
Interleukin-2 (IL-2) is a cytokine produced by activated T cells in response to antigen stimulation. IL-2 is important for proliferation of lymphocytes, natural killer cells and macrophages and in the differentiation of CD4+ cells into Th1 and Th2 effector cells. It also has a vital role in modulating the expression of the IL-2 receptor and can facilitate B cell growth and differentiation. Anti-Interleukin-2 antibody can be used for neutralizing the bioactivity of recombinant human IL-2 as well as natural human IL-2. It can also be used in immunohistochemistry. Goat anti-Interleukin-2 antibody reacts specifically with recombinant human IL-2. The antibody exhibits less than 10% cross-reactivity with rmIL-2 and rrIL-2.
Immunogen
recombinant human IL-2.
Application
Anti-Interleukin-2 antibody can be used in western blotting and indirect ELISA for detecting recombinant human IL-2.
Biochem/physiol Actions
The antibody will neutralize the biological activity of recombinant and natural human IL-2. The antibody shows <10% cross reactivity with recombinant mouse and rat IL-2.
Physical form
Lyophilized from 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | goat |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | lyophilized powder |
| species reactivity | human |
| technique(s) | immunocytochemistry: suitable,neutralization: suitable,western blot: suitable |
| UniProt accession no. | P60568 |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... IL2(3558) |
