General description
Solute carrier family 30, member 1 (SLC30A1, ZNT1, ZRC1) is a zinc transporter involved in regulating zinc and other divalent cation flux. SLC30A1/ ZNT1 is frequently coexpressed with L-type voltage-dependent calcium channel (LTCC), a major route for zinc influx. SLC30A1/ ZNT1 is believed to regulate cellular ion (calcium, cadmium, zinc) homeostasis, at least in part, by modulating/inhibiting L-type calcium channels.
Immunogen
Synthetic peptide directed towards the middle region of human SLC30A1
Application
Anti-SLC30A1 polyclonal antibody is used to tag solute carrier family 30, member 1 for detection and quantitation by Western blotting and in plasma by immunohistochemical (IHC) techniques. It is used as a probe to determine the roles of solute carrier family 30, member 1 in divalent cation (Zn2+, Cd2+, Ca2+) homeostasis, especially in conjunction with L-type voltage-dependent calcium channels.
Biochem/physiol Actions
Anti-SLC30A1 polyclonal antibody reacts with human, canine, and pig solute carrier family 30, member 1/ZNT1 proteins.
SLC30A1 may be involved in zinc transport out of the cell.
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Other Notes
Synthetic peptide located within the following region: FCVNPCFPDPCKAFVEIINSTHASVYEAGPCWVLYLDPTLCVVMVCILLY
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | 55 kDa |
| species reactivity | human |
| concentration | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| web metadata keyword.default | Anti-SLC30A1 antibody for cellular ion studies,Anti-SLC30A1 antibody rabbit Sigma-Aldrich,Anti-SLC30A1 antibody western blot grade,Anti-SLC30A1 antibody,Anti-ZNT1 antibody for calcium channel studies,Anti-ZNT1 antibody for ion homeostasis,Anti-ZNT1 antibody,Anti-ZRC1 rabbit polyclonal antibody,SLC30A1 antibody for zinc transporter research,SLC30A1 zinc transporter antibody,Sigma-Aldrich Anti-SLC30A1 antibody for lab use,high purity Anti-SLC30A1 antibody,polyclonal Anti-SLC30A1 antibody for western blot,research-grade Anti-SLC30A1 antibody |
| NCBI accession no. | NP_067017 |
| UniProt accession no. | Q9Y6M5 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... SLC30A1(7779) |
