产品介绍
Product Description
General description
The antibody pair provided in this kit recognizes Human Tyrosine-Phosphorylated-JAK2. The JAK2 (Janus kinase 2) gene is mapped to human chromosome 9p24.1.
Application
请参考Protocol了解详情。
Biochem/physiol Actions
Janus kinase 2 (JAK2) mediates epithelial-mesenchymal transition in hepatocellular carcinoma. The JAK2/STAT3 signaling pathway is associated with tumor development in a number of cancer such as gastric cancer. Mutation in the JAK2 gene is known to activate JAK2 receptor action even in the absence of ligand, inducing cell proliferation and opposing apoptosis.
技术参数
Specifications
| species reactivity | human |
| technique(s) | ELISA: suitable |
| assay range | inter-assay cv: <10% intra-assay cv: <12% |
| shipped in | wet ice |
| storage temp. | −20°C |
| Gene Information | human ... JAK2(3717) |
