General description
Lectin galactoside-binding soluble 3 binding protein (LGALS3BP), a tumor-secreted antigen, is a large oligomeric and highly glycosylated protein. The LGALS3BP gene is located on human chromosome 17q25.
Immunogen
LGALS3BP purified recombinant protein
Biochem/physiol Actions
Lectin galactoside-binding soluble 3 binding protein (LGALS3BP) also known as Mac-2 binding protein (M2BP) acts as a ligand of the lactose-specific S-type lectin, galectin-3. Mac-2 binding protein (M2BP) participates in cell adhesion and in tumor progression. Serum Mac-2 binding protein glycosylation isomer (M2BPGi) is considered as an important marker to study the criticality of liver disease.
Physical form
Solution in Dulbecco′s Modified Eagle′s Medium with 10% fetal calf serum and 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog, our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| conjugate | unconjugated |
| Quality Segment | 200 |
| antibody form | culture supernatant |
| antibody product type | primary antibodies |
| clone | LGALS3BP-A265, monoclonal |
| form | aqueous solution |
| mol wt | antigen predicted mol wt 65.2 kDa |
| species reactivity | human |
| technique(s) | western blot: suitable |
| isotype | IgG1 |
| UniProt accession no. | Q08380 |
| shipped in | dry ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... LGALS3BP(3959) |
