产品介绍
Product Description
Application
Isoetharine mesylate salt has been used:
- as an adrenergic drug to test its effect on embryo implantation in 4-day pregnant mice
- as a substrate for recombinant human sulfotransferase (SULT) in SULT assay to monitor conjugation reaction
- as a β-2 agonist in collision-induced dissociation (CID) mass spectrometry analysis
Biochem/physiol Actions
Isoetharine is an agonist for β-adrenergic receptors and is a bronchodilator. It is a catecholic drug metabolized by sulfotransferases and is present in human urine and plasma as a sulfated metabolite. Catechol O-methyltransferase (COMT) also mediates the methylation of isoetharine in the metabolic conjugation pathway.
Features and Benefits
This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
技术参数
Specifications
| originator | Sanofi Aventis |
| Quality Segment | 200 |
| storage temp. | 2-8°C |
| SMILES string | CS(O)(=O)=O.CCC(NC(C)C)C(O)c1ccc(O)c(O)c1 |
| InChI | 1S/C13H21NO3.CH4O3S/c1-4-10(14-8(2)3)13(17)9-5-6-11(15)12(16)7-9;1-5(2,3)4/h5-8,10,13-17H,4H2,1-3H3;1H3,(H,2,3,4) |
| InChI key | SOYAGMVKMXZVNZ-UHFFFAOYSA-N |
| Gene Information | human ... ADRB1(153), ADRB2(154), ADRB3(155) |
