产品介绍
Product Description
General description
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
Immunogen
A synthetic phosphorylated peptide around S128 of human YAP1 (NP_001123617.1).
Physical form
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
技术参数
Specifications
| biological source | rabbit |
| Quality Segment | 100 |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | liquid |
| species reactivity | mouse, human, rat |
| concentration | 0.85 mg/mL |
| technique(s) | western blot: 1:500-1:2000 |
| UniProt accession no. | P46937 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pSer128) |
| Gene Information | human ... YAP1(10413) |
