General description
Histone acetyltransferase 1 (HAT1) is a type B histone acetyltransferase localized in the cytosol and the nucleus. The HAT1 gene is mapped on the human chromosome at 2q31.1.
Immunogen
The antiserum was produced against synthesized peptide derived from human HAT.
Immunogen Range: 331-380
Application
Anti-HAT antibody produced in rabbit has been used in western blotting (1:500) and immunofluorescence (1:250).
Biochem/physiol Actions
Histone acetyltransferase 1 (HAT1) is involved in the acetylation of lysine 5- and 12- residues at the N-terminal of the newly synthesized histone H4. This enzyme is also involved in the regulation of DNA repair in the nucleus.
Features and Benefits
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Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | antigen 49 kDa |
| species reactivity | mouse, rat, human |
| concentration | ~1 mg/mL |
| technique(s) | ELISA: 1:5000,western blot: 1:500-1:1000 |
| NCBI accession no. | O14929 |
| UniProt accession no. | O14929 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... HAT1(8520) |
