产品介绍
Product Description
Biochem/physiol Actions
Orally available, potent, and selective noncompetitive urotensin 2 receptor antagonist
Palosuran (ACT-058362) is an orally available, potent, and selective noncompetitive urotensin 2 receptor antagonist. Palosuran decreases serum glucose, cholesterol, and triglyceride levels and increases survival in a rat model of diabetes induced by streptozotocin.
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | -10 to -25°C |
| SMILES string | N3(CCC(CC3)(O)Cc4ccccc4)CCNC(=O)Nc1c2c(nc(c1)C)cccc2 |
| InChI | 1S/C25H30N4O2/c1-19-17-23(21-9-5-6-10-22(21)27-19)28-24(30)26-13-16-29-14-11-25(31,12-15-29)18-20-7-3-2-4-8-20/h2-10,17,31H,11-16,18H2,1H3,(H2,26,27,28,30) |
| InChI key | WYJCYXOCHXWTHG-UHFFFAOYSA-N |
