General description
Cluster of differentiation 28 (CD28) antigen is a co-stimulatory receptor expressed in naive T-cells. It contains a short cytoplasmic tail and two proline-rich motifs.
Immunogen
Peptide with sequence KEKHLCHTQSSPK, from the internal region of the protein sequence according to NP_031668.3
Biochem/physiol Actions
Cluster of differentiation 28 (CD28) antigen has a role in T-cell activation, proliferation, survival and function. It modulates thymic development, peripheral homeostasis and the suppressive functions of regulatory T cells. CD28 has a role in signal transduction and is involved in activating many adaptor proteins.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | goat |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| species reactivity | mouse, pig |
| technique(s) | indirect ELISA: suitable,western blot: suitable |
| UniProt accession no. | P31041 |
| shipped in | dry ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | mouse ... Cd28(12487) |
