产品介绍
Product Description
Biochem/physiol Actions
GYY4137 sodium (Na-GYY4137) is a dichloromethane-free, water-soluble sodium salt form of the slow-releasing hydrogen sulfide (H2S) donor GYY4137. Na-GYY4137 is devoid of potential off-target effects associated with the use of dichloromethane-complexed GYY4137 morpholine salt form. Morpholine is biologically active and toxic (LD50 range of 300-500 mg/kg in rodents), while dichloromethane is carcinogenic and can metabolize in vivo to carbon monoxide, causing unintended CO-dependent effects.
Water soluble, non-toxic alternative to the dichloromethane-containing morpholine salt form of the hydrogen sulfide (H2S) donor GYY4137.
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| storage condition | desiccated |
| color | white to beige |
| solubility | H2O: 2 mg/mL, clear |
| shipped in | wet ice |
| storage temp. | −20°C |
| SMILES string | [S-]P(C1=CC=C(C=C1)OC)(N2CCOCC2)=S.[Na+] |
| InChI | 1S/C11H16NO2PS2.Na/c1-13-10-2-4-11(5-3-10)15(16,17)12-6-8-14-9-7-12;/h2-5H,6-9H2,1H3,(H,16,17);/q;+1/p-1 |
| InChI key | ZFQXKWOUNSKHAG-UHFFFAOYSA-M |
