产品介绍
Product Description
Application
MRS 1523 has been used as an inhibitor of adenosine receptors in SW1990 and BxPC3 pancreatic cancer cells, LX2 human hepatic stellate cells and human coronary smooth muscle cells.
Biochem/physiol Actions
MRS 1523 is a selective adenosine A3 receptor antagonist in the rat.
Features and Benefits
This compound is featured on the Adenosine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Legal Information
Sold under license from the National Institutes of Health
技术参数
Specifications
| Quality Level | 100 |
| assay | >98% (HPLC) |
| form | oil |
| color | colorless to light brown |
| solubility | DMSO: >10 mg/mL,H2O: insoluble |
| shipped in | wet ice |
| storage temp. | 2-8°C |
| SMILES string | CCCOC(=O)c1c(CCC)c(C(=O)SCC)c(CC)nc1-c2ccccc2 |
| InChI | 1S/C23H29NO3S/c1-5-12-17-19(23(26)28-8-4)18(7-3)24-21(16-13-10-9-11-14-16)20(17)22(25)27-15-6-2/h9-11,13-14H,5-8,12,15H2,1-4H3 |
| InChI key | UUSHFEVEROROSP-UHFFFAOYSA-N |
| Gene Information | human ... ADORA3(140) rat ... Adora1(29290), Adora2a(25369), Adora3(25370) |
