产品介绍
Product Description
Biochem/physiol Actions
Cell penetrant and potent global inhibitor of cellular glycosylation that induces reversible Golgi fragmentation.
NSC255112 is a cell penetrant and potent global inhibitor of cellular glycosylation that induces reversible Golgi fragmentation. NSC80997 affects both initiation and elongation of O-glycosylation in ways not directly dependent on GalNAc-T11. NSC255112 induces Tn antigen expression in human cell lines. It also reduces cell surface heparan sulfate a necessary factor for SARS-CoV-2 infection.
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥90% (HPLC) |
| form | powder |
| color | , Light red to dark purple |
| solubility | DMSO: 2 mg/mL, clear (Warmed) |
| storage temp. | -10 to -25°C |
| SMILES string | O=C(C(NC(/C(C)=C/C=C\[C@H](OC)[C@H]1OC(N)=O)=O)=C2/C=N/N3CCOCC3)C(C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C1\C)=C(OC)C2=O |
| InChI | 1S/C34H48N4O10/c1-19-15-23-29(40)27(24(30(41)32(23)46-7)18-36-38-11-13-47-14-12-38)37-33(42)20(2)9-8-10-25(44-5)31(48-34(35)43)22(4)17-21(3)28(39)26(16-19)45-6/h8-10,17-19,21,25-26,28,31,39H,11-16H2,1-7H3,(H2,35,43)(H,37,42)/b10-8-,20-9-,22-17-,36-18+/t19 |
| InChI key | NBLSLHGULNLUQD-PRIZTHDISA-N |
