产品介绍
Product Description
General description
ALOX5AP is a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation.
Immunogen
ALOX5AP (NP_001620, 91-127)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human ALOX5AP.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
技术参数
Specifications
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | saturated ammonium sulfate (SAS) precipitated |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| species reactivity | human |
| technique(s) | immunohistochemistry: 1:50-1:100,indirect ELISA: 1:1000,western blot: 1:100-1:500 |
| NCBI accession no. | NP_001620 |
| UniProt accession no. | P20292 |
| shipped in | dry ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... ALOX5AP(241) |
