产品介绍
Product Description
Application
L-741,626 has been used as selective dopamine (D2) receptor antagonist to study its effects on the uptake of dopamine in human embryonic kidney 293 (HEK293) cells. It has also been used as a D2 receptor antagonist to study its effects on thyrotropin-releasing hormone (TRH) induced prolactin release.
Biochem/physiol Actions
L-741,626 is a selective dopamine (D2) receptor antagonist.
Features and Benefits
This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
技术参数
Specifications
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: ≥20 mg/mL,ethanol: 24 mg/mL,H2O: insoluble |
| storage temp. | room temp |
| SMILES string | OC1(CCN(CC1)Cc2c[nH]c3ccccc23)c4ccc(Cl)cc4 |
| InChI | 1S/C20H21ClN2O/c21-17-7-5-16(6-8-17)20(24)9-11-23(12-10-20)14-15-13-22-19-4-2-1-3-18(15)19/h1-8,13,22,24H,9-12,14H2 |
| InChI key | LLBLNMUONVVVPG-UHFFFAOYSA-N |
| Gene Information | human ... DRD2(1813), DRD3(1814), DRD4(1815) |
