产品介绍
Product Description
General description
CDCA8 is a component of the chromosomal passenger complex (CPC) required for stability of the bipolar mitotic spindle. The CPC complex, a key regulator of mitosis, has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, CDCA8 may be required to direct the CPC to centromeric DNA.
Immunogen
CDCA8 (NP_060571, 120-154)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human CDCA8.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
技术参数
Specifications
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | Ig fraction of antiserum |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| species reactivity | human |
| technique(s) | immunohistochemistry: 1:50-1:100,indirect ELISA: 1:1000,western blot: 1:100-1:500 |
| NCBI accession no. | NP_060571 |
| UniProt accession no. | Q53HL2 |
| shipped in | dry ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... CDCA8(55143) |
