产品介绍
Product Description
Biochem/physiol Actions
CB2 Cannabinoid receptor agonist
HU-308 is a potent, selective agonist of the cannabinoid receptor CB2. The Ki values for CB2 vs. CB1 are 22.7nM and >10 mM, respectively. HU-308 has anti-inflammatory and neuroprotective properties, and reduces liver damage in a hepatic ischemia/reperfusion injury model.
技术参数
Specifications
| Quality Level | 100 |
| assay | ≥95% (HPLC) |
| optical activity | [α]/D 180.0 to 130.0°, c = 0.5 in chloroform-d |
| storage condition | desiccated |
| color | white to dark beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | −70°C |
| SMILES string | CCCCCCC(C)(C1=CC(OC)=C(C(OC)=C1)[C@]2(C=C([C@@H]3C(C)([C@H]2C3)C)CO)[H])C |
| InChI | 1S/C27H42O3/c1-8-9-10-11-12-26(2,3)19-14-23(29-6)25(24(15-19)30-7)20-13-18(17-28)21-16-22(20)27(21,4)5/h13-15,20-22,28H,8-12,16-17H2,1-7H3/t20-,21+,22-/m0/s1 |
| InChI key | CFMRIVODIXTERW-BDTNDASRSA-N |
