General description
Cytochrome P450 family 26 subfamily A member 1 (CYP26A1) is encoded by the gene mapped to human chromosome 10q23.33.
The previously assigned protein identifier Q5VXI0 has been merged into O43174. Full details can be found on the UniProt database.
Immunogen
CYP26A1 (NP_000774, 123-157)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human CYP26A1.
Biochem/physiol Actions
Cytochrome P450 family 26 subfamily A member 1 (CYP26A1) is a retinoic acid (RA) degrading enzyme. It plays a vital role in RA metabolism. CYP26A1 has an essential role in the correct anteroposterior patterning and the generation of migratory cranial neural crest cells in the developing mammalian brain. Mutations in the gene is associated with the pathogenesis of optic nerve aplasia (ONA).
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | saturated ammonium sulfate (SAS) precipitated |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| species reactivity | human |
| technique(s) | indirect ELISA: 1:1000,western blot: 1:100-1:500 |
| NCBI accession no. | NP_000774 |
| UniProt accession no. | O43174 |
| shipped in | dry ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... CYP26A1(1592) |
