产品介绍
Product Description
General description
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Immunogen
A synthesized peptide derived from human Mono-methyl-HIST2H2BE (R79)
Physical form
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Preparation Note
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Other Notes
AS-R(Me)-LAH
技术参数
Specifications
| recombinant | expressed in HEK 293 F cells |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody product type | primary antibodies, primary antibodies |
| clone | 3E12, recombinant monoclonal |
| form | liquid |
| mol wt | 150 kDa |
| purified by | affinity chromatography |
| species reactivity | mouse, human |
| concentration | 0.65mg/ml |
| technique(s) | ELISA: 2000:10000,flow cytometry: 1:50-1:200,immunofluorescence: 1:50-1:200,immunohistochemistry: 1:50-1:200 |
| isotype | IgG |
| UniProt accession no. | Q16778 |
| shipped in | wet ice |
| storage temp. | -10 to -25°C |
| target post-translational modification | monomethylation (Arg79) |
