Anti-SUMO 2/3 Magnetic Beads，1ML，SAE0221-1ML，Sigma

General description

The Anti-SUMO 2/3 Magnetic Beads are specialized magnetic agarose beads designed for the purification and study of SUMO (Small Ubiquitin-like Modifier) tagged fusion proteins. These beads are essential for researchers looking to explore protein interactions and functions, particularly when specific antibodies are unavailable. With a binding capacity of 600-7000 µg of SUMO2/3-tagged proteins per 1 mL of settled resin, these beads provide a reliable solution for immunoprecipitation and immunoaffinity purification.

Application

The Anti-SUMO 2/3 Magnetic Beads are ideal for a variety of applications in molecular biology and biochemistry, including:

• Protein Purification: Efficiently isolate SUMO2/3-tagged proteins from complex mixtures, such as cell lysates.
• Protein Interaction Studies: Analyze protein-protein interactions and study the topology of proteins within cellular contexts.
• Characterization of Low Abundance Proteins: Identify and characterize newly discovered proteins that are poorly immunogenic or present in low abundance.
• Cell Biology Research: Study SUMOylation processes, which play critical roles in cellular functions such as nuclear transport, transcriptional regulation, and apoptosis.

Features and Benefits

• High Specificity: The monoclonal anti-SUMO2/3 antibody specifically recognizes SUMO2/3-tagged fusion proteins, ensuring accurate results in your experiments.
• Robust Binding Capacity: With the ability to bind 600-7000 µg of SUMO2/3-tagged proteins, these beads are suitable for a wide range of sample types and concentrations.
• Convenient Magnetic Separation: The magnetic properties of the beads allow for easy separation and purification of target proteins, streamlining your workflow.
• Versatile Use: Suitable for use in various applications, including SDS-PAGE analysis, to confirm the presence of SUMO2/3-tagged proteins in your samples.

Preparation Note

To maintain optimal performance, store the Anti-SUMO 2/3 Magnetic Beads at 2-8 °C. It is crucial to avoid freezing the product, as this may affect its stability and functionality. For continuous use, ensure that the beads are mixed thoroughly before each use by gentle vortexing or inversion.